Serie A 2025-26 Matchday 16 Predictions and Picks

The Italian Serie A league continues to amaze the fans with its flamboyance. Whenever the teams pull up with their winning spirit, either of these two things happens. A dominant victory or a tightly-contested draw. This time, the same energy is back on the teams as the dramatic Serie A week of Matchday 16 arrives. As Matchday 16 approaches, the fixtures are exciting the fans, which in turn has created expectations and predictions. For these games, we have provided detailed matchup analysis and previews. We have also given Serie A odds and predictions for the four games on Matchday 16. So, choose the winning side deliberately with our expert picks. Bettingpremier gives regular updates on Serie A and every other major football league. Make sure you follow Bettingpremier to get all the latest information. You can also get news on other sports, such as basketball, baseball, and ice hockey.

Serie A Previous Games

Matchday 20 had impressive outcomes with several surprises and disappointments. Four notable draws took place that day. In particular, the Inter Milan vs Napoli game was a serious and closely contested draw. The previous year’s champions were good at equalizers for every lead Inter Milan takes. Scott McTominay is the powerhouse scorer, whose brace saved the team from losing further in the points table. Similarly, Fiorentina and AC Milan had such a close contest after a goalless first half. It was a disappointment for AC Milan to have a draw against a poor team in the league. Moreover, Atalanta had a clean sheet win against Torino. They scored a goal in both halves and tried not to concede. Their defensive spirit manifested in the form of excellent saves, blocks, and steals. Matchday 20 was highly entertaining indeed, with some riveting matchups. More football commentaries at Bettingpremier.

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Serie A Predictions & Odds for Matchday 16

Napoli vs Parma

Parma visits Napoli on 14 January 2026. This football game is set to start at 12:30 p.m. ET at the Diego Armando Maradona Stadium.

Standings

Napoli stands at 3^rd place in the Serie A standings.

Parma ranks 14^th in the current season standings.

Napoli’s Form

Napoli has a far better record than Parma, and they are currently in the third position. With their above-average league record, Napoli can singlehandedly outscore Pama. Notably, their defense is the undeniable factor that allows them to effectively block every possible goal. Out of 19 games, they have won 12 and drawn 3. With four losses, Napoli is completely alright and strong enough to pierce through Parma. Regarding the players, their squad has numerous players who excel in ball movement. The coordination and team chemistry are surprisingly good. This will enable them to generate a substantial number of goals needed in the first quarter. 

Parma’s Form

On the other hand, Parma comes with a relatively lower league rank and performance. Their current form is one of the below-average performances this season. They struggle to create and keep a momentum, often losing games and failing to generate a steady momentum. Compared to Napoli, Parma has poor offensive stats. Carlos Cuesta’s men have shown an underwhelming coordination. They often expose their possessions, creating vulnerabilities that lead to their loss. Besides, their playmaking skills are somewhat good, but this is not enough for them. Given the fact that they play away against Napoli, it is expected to be a difficult game for Parma.

Prediction

Considering the possibilities, it is apparent that Parma will likely struggle in this game against Napoli. Therefore, Napoli will win in this Serie A game.

Inter Milan vs Lecce

Inter Milan and Lecce meet each other for a thrilling matchup on 14 January 2026 at San Siro, Milan. This Serie A game will begin at 02:45 p.m. ET.

Standings

Inter Milan is the first-ranked team in the current season.

Lecce is struggling at the bottom of the league standings in 16th place.

Inter Milan’s Form

Inter Milan is undoubtedly one of the all-time elite teams in the league. Their performances this season have been simply outstanding, and they have been maintaining that since Matchday 1. Regarding their current form, Inter Milan leads nearly every major aspect. Defensively, they have the best squad with the highest goals differential in the league. They have conceded only 17 goals while scoring 42, a tremendous offensive front and a consistent scoring form. Most importantly, they remain unbeatable for the last five games. They have won in 4 of them and drawn one. This shows their strong quality in the current season. Particularly, when it comes to San Siro, they get even stronger in terms of both scoring and defense. So, the odds are in their favor.

Lecce’s Form

Lecce appears not to have a chance against Inter Milan. Their game is comparatively at a poor spot, having an underwhelming league performance. Out of 19 games, they have won only 4; they have lost the most games, along with two other teams. One of their biggest concerns is their poorest scoring side and weakest defense combined. They have scored only 13 goals over 19 games, and mostly their games were goalless defeats. On the defensive side, they have failed on multiple occasions to defend and have conceded around 27 goals. So, Lecce won’t have an easy match against Inter Milan on the road.

Prediction

Given Lecce’s poor form, Inter Milan will win in this Serie A clash.

Verona vs Bologna

Verona will face Bologna on 15 January 2026 in Serie A Matchday 16 at Marcantonio Bentegodi Stadium. This football tournament will begin at 12:30 p.m. ET.

Standings

Verona stands as the last-ranked team in the league, in 20^th place.

Bologna ranks 9^th in the current Serie A season standings.

Verona’s Form

Verona is currently the last-ranked team in the league, with one of the poorest records, having won only twice. With around 10 losses, Verona is dealing with consistency issues regarding both scoring and defense. Defensively, they have the highest goals conceded this season, allowing 31 goals so far. With a severely lacking form, Verona shows no sign of hope this season. They occasionally fail to execute quality chances. They are also poor in playmaking, which might hamper them from scoring as substantially as they need. This, in turn, would affect their overall scoring in the table as well. Even though they get a home advantage this time, the chances are really low, and the odds are against them.

Bologna’s Form

Bologna is far better than Verona. They are comfortable at 9^th position, unlike Verona, which struggles with a severe relegation risk. Bologna has won around seven games and drawn six. This is impressive and better when compared with Verona’s poor record. Bologna has a positive goal differential, indicating a solid defensive side. Technically, they have a flexible formation, and their playmaking sustains under pressure. Additionally, they create pressure in the opening moments to exploit their opponents’ lapses. All their strengths perfectly complement Verona’s weaknesses.

Prediction

Bologna is predicted to win in this Serie A game.

Como vs AC Milan

Como will face AC Milan in the upcoming game on 15 January 2026. This Serie A game will begin at 02:45 p.m. ET at the Stadio Comunale G. Sinigaglia.

Standings

Como is in the 6^th spot in the current standings.

AC Milan is trailing behind Inter Milan at the 2nd rank.

Como’s Form

Como comes with a good winning probability in this game. They have a solid record of 9-7-3 and are above average in both scoring and defense. They have scored 27 goals and conceded only 23 so far. Their last five games have been particularly consistent, having three consecutive wins and a draw. They also have improved ball movement and passing. Their passing and assists are more organized lately. Strategically, they prefer to pressure early in the game. However, they do show some setbacks, especially against elite teams. They often fail to concede or to chase the target. This is a minor concern, which might reduce their likelihood of winning.

AC Milan’s Form

AC Milan is a top-tier team currently playing in the league. They have the second-best record, but still by a substantial margin. They have remained unbeatable for the past five games, indicating their quality and consistency. Their defense is a notable trait as they have allowed only 15 goals, while bagging 30 goals. Under Paulo Fonseca, their 4-2-3-1 formation allows them to attack based on possession. Their midfield control is above average and most likely to be pivotal in crucial situations. Additionally, they have quick-paced movements and excellent coordination. With this, they excel at creating chances and executing them flawlessly.

Prediction

Given both teams’ strengths and weaknesses, AC Milan is more likely to win.