Serie A 2025-26 – Matchday 12 Preview

The Italian Serie A game has been hitting viewers with a visceral punch from day 1. Every game was genuinely a sensation. Particularly, the games forced every team to find the right momentum and fight for points in the table. Moreover, the Italian football league has another layer of narrative, the relegation risk. The relegation zone is a looming threat to every team at the bottom of the table. Moreover, the games were tremendously entertaining on the previous matchday. Now we are getting near the Serie A Matchday 12 with the most-awaited Derby di Milano. The Milan Derby is the most expected as both clubs are just a position away in the table. So, fans can deliberately expect more dramatic moments. Regarding the standings, the table has Inter Milan at the top, followed by Roma, AC Milan, and Napoli, respectively. Get up-to-date news and Serie A sensations exclusively from Bettingpremier.

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Serie A Matchday 11 – Notable Incidents

Serie A Matchday 11 was an interesting case that every football fan must study. That matchday left everyone speechless as it was only either clean-sheet wins or draws. 50% of fixtures were clear draws, and the remaining 50% were clean-sheet outcomes. Two out of five draws were 2-2 ties. The remaining three were goalless draws. Genoa, Fiorentina, Parma, and Milan tied with two goals each. On the other hand, clubs like Juventus, Torino, Lecce, Verona, Como, and Cagliari drew goalless. Only Sassuolo achieved a dominant victory against Atalanta. They scored three goals, with Domenico Berardi scoring 2. Likewise, Inter Milan scored twice against Lazio, exploiting their weak defense. Similarly, Bologna beat Napoli and Roma beat Udinese by 2-0. Pisa had a hard-fought battle against Cremonese, which they won by a single score in the second half. Stay up to date on the latest football news from Bettingpremier.

Expectations for Upcoming Matchday

Among all the news, the Derby di Milano is the most interesting event of Matchday 12. The Derby della Madonnina holds a significant weight in the next set of clashes. Historically, Milanese clubs’ clashes have had high fan engagement. Considering their league positions, both clubs will be fierce in their pursuit of victory. In addition, several more clashes are listed in the schedule. Napoli vs Atalanta, Cremonese vs Roma, and Fiorentina vs Juventus are some critical draws. Moreover, their chances of winning, losing, or drawing are detailed below.

Serie A Odds and Predictions for Upcoming Games

Pick your favorite match and choose a side. Bettingpremier’s expert predictions have given odds and picks for the upcoming Serie A Matchday 12. Follow up with Bettingpremier to get detailed sports predictions and betting insights.

Cagliari vs Genoa

Cagliari takes on Genoa at the Unipol Domus on 22 November 2025. Expect this Serie A game to start at 09:00 a.m. ET.

Cagliari Calcio

Cagliari’s previous match ended tragically in a home loss. They haven’t got a chance to score a single goal. Inter Milan totally strangled them with their explosive offensive pressure. Their last match’s result still lingers with the team as they head into a clash against Genoa. They employ a 3-5-2 formation and frequently switch between 4-3-1-2 and 4-4-2. However, their recent form is mixed with losses, draws, and wins. Overall, the team has shown an ability to score and draw.

Genoa CFC

Genoa is at the league’s bottom with only one win. Although the difference is not huge, Genoa is struggling to outscore its opponents. Their average score is below one as they have scored only eight goals so far in the league. This is close to Cagliari’s nine goals out of 11 games. Their most recent formations, such as the 4-2-3-1, have yielded poor results. This game will be a tight contest. However, considering both sides, Cagliari has a slight edge to win this time, given its home advantage.

Prediction

Cagliari will secure a triumph at home this time.

Udinese vs Bologna

Set yourselves up for a great rivalry at the Bluenergy Stadium on 22 November 2025. This Udinese vs Bologna clash will start at 09:00 a.m. ET.

Udinese Calcio

Udinese Calcio is currently ranked 10th in Serie A this season, with 15 points. They have scored 12 goals in 11 games this season. However, they conceded more than they scored overall. This shows their average defensive side, which fails to protect the net. Playing at home this time, Udinese gets balanced support, which may help them to go for a while.

Bologna FC 1909

Bologna, on the other hand, is in far better form. They have scored 18 goals in 11 games. With a fifth-place finish in the league, they have a prolific offense and defense. They have conceded only eight games while scoring 18. This shows their elite overall form. Their compact formation allows them to protect their back while creating chances. However, they may face slight opposition from Udinese’s home form. Yet, they have the overall advantage.

Prediction

Bologna will win in this Serie A game.

Fiorentina vs Juventus

Fiorentina is set to face Juventus on 22 November 2025 at the Artemio Franchi Stadium. This Serie A game will start at 12:00 p.m. ET.

AFC Fiorentina

AFC Fiorentina has not won a single game in this league, having played 11 games to date. They have drawn six games and lost five. Fiorentina uses the 3-5-2 formation more frequently. However, they never had any luck in any league games. Staying at the relegation risk, their league form has suffered from underwhelming performances. With a 20^th rank in the table, Fiorentina is looking for redemption. Both their defensive and offensive sides are too weak. They have conceded twice as many as they score in their recent games. Their home venue is also not a positive factor, as they have not won at home this season.

Juventus FC

On the contrary, Juventus FC is ranked at the table’s bottom with a good league run. Compared to Fiorentina, they are in better form overall. Their offense is good if not exceptional. They score sparingly as needed; they mainly focus on defending. With five wins and four draws, Juventus shows a lower likelihood of defeat. Their scoring and defense are good on the road, indicating their winning probability in this game.

Prediction

Juventus FC will win in this Serie A game.

Napoli vs Atalanta

Napoli and Atalanta will play in the upcoming game on 22 November 2025. This Serie A game will start at 02:15 p.m. ET at Diego Armando Maradona Stadium.

SSC Napoli

Napoli has a good league run with 4^th place in the standings. They won seven times, drew once, and lost three times. With 22 points in the table, Napoli brings its superior form and dominance to the game. Although their offense is solid, scoring frequently, their defense is weak, as they have conceded 10 goals this season. With a good home record, Napoli arrives with confidence against a struggling Atalanta.

Atalanta BC

Atalanta BC is more like a struggling star trying hard to find a momentum they can sustain. Unfortunately, their efforts yield no benefit given their average league position. Their offense is decent, but their defense is poor, allowing goals against the team. They are more prone to draw matches, having drawn seven games. This is the highest ever for a Serie A team this season. But their poor season form is of no use in an away game against Napoli. Hence, Napoli has the winning edge.

Prediction

Napoli will win at home in this Serie A game against Atalanta.

Verona vs Parma

Parma will face Verona in this Serie A game on 23 November 2025 at Marcantonio Bentegodi. The game starts at 06:30 a.m. ET.

Hellas Verona FC

Hellas Verona is terrible this season, with a poor league record and a 19th-place finish. Verona has not won a single game this season and is hoping to win their next match. They have drawn six games and lost five this season, accumulating six points. Their most significant setback is their poor defense. They have conceded 16 goals while scoring only six times. This is too weak for a team in the league. However, their home field may give them a slight boost as they face Parma.

Parma Calcio 1913

Parma’s current form is not good either. They are just a rank above getting relegated. Their overall score is 7 out of 11 games so far. However, their defense is much better than Verona’s. They also have a better scoring output, having scored more than the hosts. But in away games, Parma’s defense will become vulnerable. However, their overall form is slightly better than Hellas Verona’s. Hence, Parma Calcio has a winning advantage.

Prediction

Parma Calcio will win in this game against Hellas Verona.

Cremonese vs Roma

Roma will visit Cremonese at Giovanni Zini Stadium on 23 November 2025. The game will begin at 09:00 a.m. ET.

US Cremonese

Cremonese has an underwhelming league performance, with only three wins, five draws, and three losses. Their form is unbalanced, as they have conceded more than they have scored. The team has scored only 12 goals while allowing 13 goals. Although this indicates a weak defense, Cremonese performs well at home. Their formation will enable them to create chances. But they occasionally fail to capitalize on their chances. Additionally, AS Roma has a comparatively better form and record this time.

AS Roma

AS Roma arrives in top form. They are currently in second place in the league. With an above-average league position, AS Roma has all the factors to win in this game. Roma’s offensive stats are far better than Cremonese’s. Roma has scored 12 goals while conceding only five. This shows their balanced offense and defense. Mainly, their formation provides the team with strong protection. Playing at the Giovanni Zini Stadium, Roma will have to work hard to control Cremonese. However, Roma’s good away form will enable them to contain Cremonese.

Prediction

AS Roma will outscore Cremonese in this Serie A game.

Lazio vs Lecce

Lecce is all set to face Lazio at home on 23 November 2025. This Serie A game will begin at 12:00 p.m. ET at Olimpico Stadium.

SS Lazio

Lazio is better than Lecce this season. They have a 4-3-4 record with reasonable form. Their offensive form is good, with an average of at least 1 goal per match. They also have a good defense as they concede economically. At home, Lazio appears to be in good form with an impressive record. Historically, Lazio has always dominated Lecce. With a better chance at winning, Lazio shows readiness to wear down Lecce.

US Lecce

Lecce primarily plays a 4-2-3-1, but has had a poor league run. Currently sitting in 15^th spot, Lecce’s game is not as impressive as Lazio’s. Their recent games were underwhelming on offense. In addition, they have had frequent goalless defeats even at home games. This shows their inefficiency on the road. Regarding scoring, they have scored only eight goals across 11 league games, indicating their poor scoring form. On top of all, they are visiting the home team, playing away this time. This is a significant concern for Lecce as they have lost away matches more frequently.

Prediction

SS Lazio will win in this Serie A game.

Inter Milan vs AC Milan

Inter Milan and AC Milan will play in the upcoming Derby di Milan on 23 November 2025. The game will start at 02:45 p.m. ET at San Siro Stadium.

Inter Milan

Inter Milan is currently the league’s leading team. They have the league’s best record, having won eight games and lost three. With 24 points in the league, their scoring is enormous, scoring 26 goals in 11 matches. This shows how prolific they are at finding net. They also have a good defense. But compared to AC Milan, they have conceded more goals this season. Historically, they have a good record at San Siro. Regarding H2H records, Inter Milan has the upper hand with 32 wins. In short, Inter Milan has the prospect despite it being a close contest.

AC Milan

AC Milan comes to this Derby di Milan with a strong league record, coming close to replacing Inter Milan. They won in six games and drew four with only one loss. AC Milan is determined to win in this upcoming Derby with their reluctance to lose. They have a more balanced form that has scored 17 goals while allowing only nine goals. However, playing away, the odds are against AC Milan.

Prediction

Inter Milan will win in this Serie A contest against AC Milan.                      

Torino vs Como

Como 1907 will visit Torino FC on 24 November 2025 at Olympic Grande Torino Stadium. This Serie A event begins at 12:30 p.m. ET.

Torino FC

Torino sits in 12^th spot with an average record. With a typical 3-4-2-1 formation, they prefer a high-pressing and aggressive approach. However, the team has a poor defensive front. They have conceded in nearly every game they played this season. All this while they still scored only 10 goals so far. Although their scoring is concerning, Torino’s home stadium might give them an edge in this game.

Como 1907

On the other hand, Como comes with a superior league performance and record. They have lost only one game, having won four and drawn six. With 18 points in the league table, Como boasts its better overall form. Mainly, their defense is robust as they have conceded only six goals so far. This is one of the fewest goals conceded in the league.

Prediction

Como is predicted to win in the Serie A game.

Sassuolo vs Pisa

Sassuolo hosts the upcoming Serie A game, welcoming Pisa on 24 November 2025. The match kicks off at 02:45 p.m. ET at Mapei Stadium.

US Sassuolo Calcio

Sassuolo is ranked higher than Pisa in scoring, defense, and other tactics. They come in at 8th in the league, having gained 16 points overall. Although they concede as many goals as they score, Sassuolo’s overall form is better than Pisa’s. With a good home record, Sassuolo will benefit from its home advantage this time.

Pisa SC

Pisa, on the other hand, is having a tough time finding momentum. They have won only once this season. But they draw more frequently with six draws and four defeats. However, their form is unbalanced, with eight goals scored and 14 conceded. Playing away this time, Pisa will find it difficult to beat Sassuolo.

Prediction

Sassuolo will win in this Serie A home game.