American Football

NFL Week 12 Predictions – A Detailed Preview and Analysis

The National Football League’s flamboyant matches are here with the Week 12 games. League’s top teams, like the Packers, Patriots, Colts, and Bills, are playing fierce games this time. Particularly, rivalries like Lions vs Giants, Bears vs Steelers, and Cowboys vs Eagles are the cherry on top. You can literally see the fighting spirits in their game. For every rush and touchdown, fans will go wild. With every matchup, you will have the excitement increasingly culminating towards Super Bowl events. Every team is trying to leave a legacy behind. No one is ready to accept failures. Therefore, there is no room for disinterest this weekend. The weekend is all yours. Choose your side and enjoy every NFL game. By the way, Bettingpremier has given you a detailed game breakdown and predictions. With our exclusive preview, you can get the latest NFL schedules and predictions from us.

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Previous Games Highlights

The New England Patriots put on quite a show last week. They contained the Jets for 14 points and won by scoring 27. The New York Jets scored a touchdown in the first quarter. However, the Patriots scored two touchdowns in the second quarter while restricting them. After that, they continued to score touchdowns. The Jacksonville Jaguars beat the Los Angeles Chargers by a commanding margin. They vigorously defended and strangled the Chargers, allowing only two field goals. Meanwhile, the Jaguars scored five touchdowns, which showed their outstanding running game. Similarly, the Philadelphia Eagles won over the Detroit Lions by a narrow margin. The Eagles scored only one touchdown against the Lions’ strong defense. They added three more touchdowns in addition. In contrast, the Lions scored only one touchdown and two field goals. Concisely, Week 12 was incredibly entertaining, though. Follow Bettingpremier to get more American football breakdowns.

Future Games and Expected Outcomes

You can expect absolute entertainment from this NFL 2025-26 season. Especially, the Bears vs the Steelers clash poses a tight contest. Both teams are performing well on the ground, with solid running games and defenses. So, this match is highly unpredictable. Next, the Bengals vs the Patriots game is another clash featuring two teams with significant contrasts. The New England Patriots have an excellent league record, while the Cincinnati Bengals are underwhelming with a 3-7 record. This match is a chance for the Bengals to gain some momentum. But the Patriots’ current form and momentum won’t allow the Bengals to defeat them. We can expect a great running game from both sides this time. In particular, Drake Maye’s performance is eagerly awaited. Several other games, like 49ers vs Panthers and Cardinals vs Jaguars, are building anticipation beyond the main narratives. Get access to Bettingpremier’s exclusive sports updates and sensational news.

NFL Week 12 Predictions

Texans vs Bills

The Buffalo Bills will take on the Houston Texans on 20 November 2025. This NFL Week 12 game will start at 08:15 p.m. ET at NRG Stadium.

Houston Texans

The Texans had a good season the previous year, finishing 10-7. Their talented young core and key veterans. However, Quarterback CJ Stroud had an injury in week 9. While he was on the roster, his presence boosted the team’s offense. However, his sustained injury and absences have left a void in the team’s offensive front. Replacing Stroud, David Mills unleashed his running game in two matches. His efficiency, however, is mixed and less consistent than Stroud’s. But their defensive unit still looks promising, with good stats. They remain competitive solely through their defense. With home advantage, they are expected to face the Bills confidently.

Buffalo Bills

The Buffalo Bills have a good league record, currently winning 7 out of 10 games. Their performance was strong in the opening games, showing their elite offensive power. Quarterback Josh Allen is their biggest strength with MVP potential. They also effectively avoid turnovers with good defensive stats. With a recent win against the Buccaneers, the Buffalo Bills bring their winning momentum to this away game.

Prediction

The Buffalo Bills will undoubtedly wear down the Texans in this NFL game.

Chiefs vs Colts

The Kansas City Chiefs will host the Indianapolis Colts in the upcoming game. This game will start at Arrowhead Stadium on 23 November 2025 at 01:00 p.m. ET.

Kansas City Chiefs

The Kansas City Chiefs have an explosive offense led by Patrick Mahomes’ MVP-caliber play. They also have a strong defensive side that consistently ranks in the top 10 in the league. Patrick Mahomes’s quarterback efficiency is spot-on in his excellent yardage this season. Regarding the running game, Kareem Hunt and Isiah Pacheco’s duo is outstanding. This is especially effective only in short-yardage situations. But they have encountered recent struggles, as evidenced in their last game against the Broncos. However, the difference was negligible. In addition, they have a reasonably decent home record. Getting a home record this time, the Chiefs are expected to protect their offense from the Colts.

Indianapolis Colts

The Indianapolis Colts have an elite record of 8-2. This season, their success is primarily attributed to running back Johnathan Taylor. Currently, the Colts are ranked first in every league category. They showed an outstanding performance this season. The Colts are also the NFL’s number 1 offense this season. Quarterback Daniel Jones is a key offensive threat to their opponents. In short, the Colts have the winning edge.

Prediction

The Indianapolis Colts will win in this NFL game.

Packers vs Vikings

The Minnesota Vikings are clashing with the Green Bay Packers in the upcoming NFL game on 22 November 2025. This clash will start at Lambeau Field at 01:00 p.m. ET.

Green Bay Packers

The Green Bay Packers have an outstanding defense that keeps opponents trying harder. Although they went offensively weak in several matches, they have compensated with their rigid defensive front. It keeps them competitive in every game they play. In addition, they have also shown an improvement in turnovers. They force more turnovers in recent games. Quarterback Joran Love is solid, just as usual. With a home advantage, the Green Bay Packers are ready to go.

Minnesota Vikings

The Vikings arrive with an average league. They have a 4-6 record, indicating a weak overall form. Their defense is weak as they have allowed more points than they score. Even at home, the team has won only one of five games. They are also weak on the road. Rookie QB J.J. McCarthy shows occasional potential. But his unreliable play makes the game ambiguous. Their running game is also inefficient, with poor yardage per carry. The Minnesota Vikings will have a tough time facing the Green Bay Packers.

Prediction

The Green Bay Packers will win in this game against the Vikings.

Lions vs Giants

The Detroit Lions face the New York Giants on 23 November 2025 at Ford Field. This NFL game will start at 01:00 p.m. ET.

Detroit Lions

The Detroit Lions are way better than the New York Giants. They have a 6-4 record that sums up their current form perfectly. Their rushing attack is the highlight, ranking sixth in the NFL. Jahmyr Gibbs and David Montgomery’s duo further confirms this with their above-average running game. Quarterback Jared Goff has been performing reliably, with numerous touchdowns and fewer interceptions. Defensively, the Detroit Lions are among the top 10 teams in the league. Although they have occasional defensive lapses, the Lions have a good chance of winning this home game. 

New York Giants

The New York Giants, on the other hand, arrive with an inferior record. Their average points per game are not as high as the Lions. Currently, the team has undergone some coaching changes and injury lists. They have been dealing with several issues with players like Jaxson Dart and Kayvon Thibodeaux. At this point, the team chemistry is falling apart. Playing on the road, the Giants will face difficulties.

Prediction

The Detroit Lions will win in this NFL game.

Bears vs Steelers

The Pittsburgh Steelers and the Chicago Bears will face off in the upcoming NFL game. This match will start on 23 November 2025 at Soldier Field at 01:00 p.m. ET.

Chicago Bears

The Chicago Bears are currently one of the best-performing teams this season. With a good league record, the Bears arrive with a solid offensive side. They have a good running game. Veteran running back D’Andre Swift’s game is exactly at its peak. His yards per carry are impressive, helping the team gain more yards overall. Quarterback Caleb Williams shows growth from his recent league performance. He has shown great resilience and composure under pressure. This time, they have a home advantage, with a good record of 3-1.

Pittsburgh Steelers

The Pittsburgh Steelers have had a good start this season. They even lead the AFC North currently. However, their current form is slightly poorer than the Chicago Bears. Their recent mixed results indicate their volatility. They heavily rely on a defense-first approach that tends to restrict a team’s scoring primarily. Additionally, Quarterback Aaron Rodgers is sidelined with an injury. As a result, they will give other veterans and rookies a chance.

Prediction

The Chicago Bears have the edge, given the Steelers’ struggling current form.

Bengals vs Patriots

Paycor Stadium sets the stage for the Cincinnati Bengals vs the New England Patriots game on 22 November 2025. This game will start at 01:00 p.m. ET.

Cincinnati Bengals

The Cincinnati Bengals have an elite offense, but are hindered by their recent injury list. Besides, their defense is also struggling, particularly against the run. Their Quarterback, Joe Burrow, is injured and sidelined. He is expected to return only in week 13. But their running game is effective with Chase Brown in the backfield. However, the team has defensive struggles. Their run defense is one of the worst in the league, ranking last. This is even more amplified with injury to key players like Cam Taylor-Britt.

New England Patriots

The New England Patriots are far better than the Cincinnati Bengals. They currently rule the league standings. With a 9-2 record, the Patriots excel both offensively and defensively. Especially, Quarterback Drake Maye is a major force in the team’s offensive front. His MVP performance is a standout strength that enables them to dismantle their opponents. Above all, their away form is excellent, indicating a readiness to upset the hosts.

Prediction

The New England Patriots will win in this NFL game.

Cardinals vs Jaguars

The Jacksonville Jaguars and the Arizona Cardinals will play in the upcoming NFL game on 23 November 2025. This American football event will start at 04:05 p.m. ET at State Farm Stadium.

Arizona Cardinals

The Arizona Cardinals are underwhelming in the current NFL season, with a 3-6 record. Their inconsistent current form is visible in their subpar running game and average defense. Moreover, they have sustained injury lists to deal with. James Conner’s injury hampers the team even more. As a result, their running game has further weakened. Quarterback Kyler Murray’s efficiency has declined when compared with their previous season. They receive a home advantage, however.

Jacksonville Jaguars

The Jacksonville Jaguars have a better record than the Cardinals. They have a 5-4 league record and an elite running game. The Jaguars rank as the 8th-best team in the running game. QB Trevor Lawrence is inconsistent with poor completion rates in several games. Defensively, the team capitalizes on the opportunities. They have a good turnover ratio, ranking 4th in the league. This time, they arrive with a 50-50 chance of winning away games.

Prediction

The Jaguars are the favorite to win in this NFL game.

Cowboys vs Eagles

Prepare to witness the clash between the Dallas Cowboys and the Philadelphia Eagles. This NFL game will begin at 04:25 p.m. ET on 23 November 2025 at AT&T Stadium.

Dallas Cowboys

The Dallas Cowboys have a disappointing record, with only three wins this season. They are facing significant challenges lately. Their offense is great, with good yards and points per game. However, their defensive side is depleted in talent. They allow more points per game. Quarterback Dak Prescott’s presence has no impact, although he shows occasional hope. But his game is unreliable. Additionally, their running game is also inconsistent.

Philadelphia Eagles

The Philadelphia Eagles have an elite record of 8-2. Their main strength is their defensive side. They effectively restrict their opponents with relatively the lowest points allowed per game in recent matches. Quarterback Jalen Hurts has an elite performance in the league. On the offensive side, the Eagles have a balanced approach that has a consistent rhythm. Both their home form and away form are perfect. They have won four of five away games, showing their ability to upset hosts.

Prediction

The Philadelphia Eagles will outscore the Dallas Cowboys in this NFL game.

Rams vs Buccaneers

The Los Angeles Rams are set to clash with the Tampa Bay Buccaneers on 23 November 2025 at SoFi Stadium. This NFL fixture begins at 08:15 p.m. ET.

Los Angeles Rams

The Los Angeles Rams have an 8-2 record this season. They have a solid home record with four wins and a single defeat at home this season. With a five-game winning streak, the Rams arrive with a top-tier form to dismantle the Buccaneers. They allow significantly fewer points than they score. With a home advantage this time, the Rams come with a good winning probability.

Tampa Bay Buccaneers

The Tampa Bay Buccaneers, on the other hand, have a similar form. They have won in 7 games and lost in 3. Their home form is average. However, they away performance is outstanding. But still, their last two games were defeats. Facing the Rams with a 5-game winning streak on the road, the Buccaneers will have difficulties.

Prediction

The Los Angeles Rams will win in this NFL game.

49ers vs Panthers

The Carolina Panthers will visit the San Francisco 49ers in the upcoming NFL game at Levi’s Stadium. This NFL game will start at 08:15 p.m. ET on 24 November 2025.

San Francisco 49ers

The San Francisco 49ers have an injury-plagued yet strong team. Their running game is superior with Christian McCaffrey’s presence. They have a 7-4 record. However, their home form is a bit concerning. With a recent win in their last game, the 49ers head to clash with the Panthers. In addition, their pass rush is their major strength, containing their opponents’ run game. This time, they are poised to take on the Panthers.

Carolina Panthers

Quarterback Bryce Young is the Panthers’ only hope. The Carolina Panthers have a 6-5 record with an average away performance. However, their last performance was a loss. Looking to bounce back from defeat, the Panthers hope to win over the 49ers.

Prediction

The San Francisco 49ers will win in this NFL Week 12 clash against the Panthers.

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