NFL 2025-26 Regular Season – Week 16 Predictions

We are only two weeks’ matches away from entering to watch the knockout stage. Several teams like the Patriots, Bills, Eagles, Bears, and Rams are eager to enter the playoffs. On the other hand, there are teams that hope they can get into the knockout stage somehow. The upcoming NFL Week 16 brings these clubs together for an intense clash and offers top-tier entertainment ahead. So, stay tuned with Bettingpremier to get up-to-date NFL updates.

In this article, we provided the NFL Week 16 schedule and predictions for the games. It includes team analysis, previous matchups, and the player squad. Without further ado, let’s dive in.

Previous NFL Game Highlights

In the NFL Week 15 matchup, several games ended, breaking several winning streaks and setting records as well. The Buccaneers, for instance, had a narrow win against the Falcons, who came close to the Buccaneers. Ultimately, consecutive scoring in all quarters earned them the victory. The Texans crushed the Cardinals with a high margin. They almost came near the Texans in the scores, but still fell short of one point. Especially, the Eagles had a threatening win against the Raiders. It was a unique game, where the Eagles restricted the Las Vegas Raiders to zero points in all quarters. There were also some other matchups that gave us a close contest. Combinedly, the NFL Week 15 matchups  were thoroughly entertaining for the fans. To get more American football commentaries like this, follow Bettignpremier.

NFL Week 16 – Schedule and Prediction

Seahawks vs Rams

The Seattle Seahawks are taking on the Los Angeles Rams on 18 December 2025. This NFL matchup will start at 08:15 p.m. ET at Lumen Field.

Seattle Seahawks’ Form

The Seattle Seahawks are currently tied with the Los Angeles Rams, standing with an 11-3 record. They are on a four-game winning streak following their earlier defeat at the hands of the Rams in a previous game. The Seahawks and the Rams have the same win percentage, making this matchup tighter. The Rams, on the other hand, are in good momentum as they can shut down opponents with a large margin. They also bring an effective running game with their Quarterback, Sam Darnold, who ranks 6^th in passing yards. His touchdown efficiency also ranks in 10^th position. In addition, wide receiver Jaxon Smith-Njigba’s receiving yards are the best in the current league. Click on Bettingpremier’s sports news to get every trending buzz on time.

Los Angeles Rams’ Form

The Los Angeles Rams are similarly matched against the Seahawks. Their Quarterback, Matthew Stafford, is highly effective in every game he plays. Above all, he ranks as the best in touchdown efficiency in the league. His passing yardage also ranks 2nd in the league with 3722 yards. It shows us their superior squad over the Seattle Seahawks. Regarding their team, they have a versatile roster, which is collectively better than the Seahawks. Although the Seahawks are similar to the Rams, the Rams have a slight advantage in the rushing game.

Verdict

The Los Angeles Rams will win over the Seattle Seahawks in this NFL matchup.

Commanders vs Eagles

The Philadelphia Eagles are visiting the Washington Commanders in the upcoming NFL game at Northwest Stadium. This game will start at 05:00 p.m. ET on 20 December 2025.

Washington Commanders’ Form

The Washington Commanders have little chance of winning this matchup, given their already poor record. They enter with a 4-10 record in the league, an underwhelming performance indeed. The Commanders’ Quarterback, Jayden Daniels, has a rushing game that is average when compared with Jalen Hurts’. But their total yards are higher than the Eagles’ counterpart, highlighting the Commanders’ squad depth. They have won only in two of their last ten games, which shows their struggling form. The Commanders average 20.8 points per game, a decent scoring average. This is slightly less than the Eagles’ 22.9 points. But their receiving yards are notably less than the Eagles’.

Philadelphia Eagles’ Form

The Philadelphia Eagles have a much superior form compared to the Commanders. Their record of 9-5 speaks volumes about the stark contrast between them and the struggling Commanders’ form. Jalen Hurts’ top form in the game is a notable strength that can boost their scoring efficiency. He has a accumulated rushing yards of 2929, higher than the Commanders’ total yardage. They also have a strong offensive line that protects their Quarterback, as they have allowed only a few interceptions. This is far better than the Commanders’ offensive line. In terms of receiving, the Eagles show a constant yardage across all games. Comparatively, the Philadelphia Eagles have a strong advantage in this NFL matchup.

Verdict

The Philadelphia Eagles will win in this NFL game.

Bears vs Packers

The Chicago Bears are facing the Green Bay Packers at Soldier Field on 20 December 2025 at 08:20 p.m. ET.

Chicago Bears’ Form

The Chicago Bears are performing well with their dominant form and 10-4 league record. Their recent games were all impressive as their touchdown efficiency and rushing game have improved significantly. But the only thing that concerns them is their previous defeat by the Green Bay Packers. In a recent clash, the Bears lost to the Green Bay Packers by one touchdown. Caleb Williams ‘ running game was notable in that game, but Jordan Love’s dominance overshadowed the Bears’ offensive efforts. But in the upcoming game, the Bears look more powerful and organized. Their average yards per game is the second-best in the current NFL season. They also lead the league in turnover stats with the highest positive goal differential.

Green Bay Packers’ Form

The Green Bay Packers arrive in good form but lack the quality to outmatch the Bears. Despite a recent win against the Bears, their scoring efficiency is slightly inferior in some aspects. But Quarterback Jordan Love’s passing yards are significantly better as he ranks 7^th in the league. However, the Packers’ defense is slightly weaker than the Bears’, which has forced more fumbles. Despite having a good rushing game, the Packers might face scoring difficulties against the Bears’ improved defense. The Bears have the overall advantage to win over the Green Bay Packers.

Verdict

Amidst a close contest, expect the Chicago Bears to win in this NFL game.

Ravens vs Patriots

The New England Patriots and the Baltimore Ravens are clashing in the NFL Regular Season’s Week 16 matchups. This rivalry begins on 21 December 2025 at M&T Bank Stadium at 08:20 p.m. ET.

Baltimore Ravens’ Form

The Baltimore Ravens’ current form is irregular, with a 7-7 record, and they are weak at home games. They allow nearly as many points as they score, indicating a not-so-laudable defense. Lamar Jackson’s rushing game is decent with 2210 yards overall. But their offensive line lacks the physicality to prevent interceptions. Their receiving yards are also substantially poorer than the Patriots’. Concisely, the Baltimore Ravens are not equipped enough to beat the New England Patriots.

New England Patriots’ Form

The New England Patriots have a stunning league record of 11-3 and a good away record. Their overall performance in away games is just as potent as their home games. With Drake Maye being a prominent scorer in the NFL, the Patriots’ rushing game has a strong offensive capability. His touchdown efficiency is one of a kind in the league. As a result, we can expect the New England Patriots to easily beat the Ravens on the road.

Verdict

The New England Patriots have the winning edge in the upcoming NFL game.

Colts vs 49ers

Prepare for the upcoming clash between the Indianapolis Colts and the San Francisco 49ers at Lucas Oil Stadium. This game will start at 08:15 p.m. ET on 22 December 2025.

Indianapolis Colts’ Form

The Indianapolis Colts’ offensive side is their biggest strength with Daniel Jones’ ball movement. Their rushing yards are also higher than the 49ers’, hinting at an offensive outperformance. Defensively, they are good at forcing errors and creating fumbles. In short, the Indianapolis Colts have a well-rounded team that excels on both offense and defense.

San Francisco 49ers’ Form

The San Francisco 49ers have a weak scoring form that is ranked at 10^th in average yards per game. Quarterback Mac Jones’s running game is decent enough to score. But the 49ers’ Quarterback and Running Back efficiency lacks the spirit to outscore the Colts. Moreover, the Colts’ balanced defense will easily stifle the 49ers’ offense. Playing on the road against the Colts, the 49ers have less probability of winning.

Verdict

The Indianapolis Colts will win in this clash against the 49ers.